Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
Healthy Volunteers
NCT04284397

Identification of Critical Thermal Environments for Aged Adults

Led by Penn State University · Updated on 2026-01-27

190

Participants Needed

1

Research Sites

321 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study evaluates critical environmental limits (temperature and humidity) above which older adults are unable to effectively thermoregulate. Participants will exercise in a series of different environmental conditions to identify combinations of temperature and humidity above which age-related physiological changes cause uncompensable heat stress, resulting in increased risk of heat illness.

CONDITIONS

Official Title

Identification of Critical Thermal Environments for Aged Adults

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 and older (those 40+ years of age must be cleared by collaborating physician)
  • All premenopausal women will be eumenorrheic (by survey)
  • Asymptomatic and no signs/symptoms of disease according to the American College of Sports Medicine 10th edition Guidelines for Exercise Testing and Prescription
Not Eligible

You will not qualify if you...

  • Medications that affect thermoregulatory or cardiovascular responses to exercise
  • Any contraindications to low intensity physical activity on the Physical Activity Readiness Questionnaire
  • Any mobility restrictions that interfere with low intensity physical activity
  • Pregnant or planning to become pregnant in the next 12 months
  • Prior diagnosis of cancer, cardiovascular disease, diabetes, or metabolic syndrome
  • Illegal/recreational drug use
  • History of Chron's disease, diverticulitis, or similar gastrointestinal disease
  • Abnormal resting or exercise electrocardiogram (ECG)

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Noll Laboratory

University Park, Pennsylvania, United States, 16802

Actively Recruiting

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Research Team

L

Lacy M Alexander, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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