Actively Recruiting
Identification of Genetic, Phenotypic, Clinical, Biological and Histological Factors Differentiating Patients With Ovarian Cancer Who Are Refractory to Platinum-based Therapy From Patients Defined as Long-term Responders to Platinum-based Therapy
Led by Centre Jean Perrin · Updated on 2026-02-20
55
Participants Needed
1
Research Sites
96 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
After having constituted the ORTRAI cohort using the CONSORE database at the Jean PERRIN Center, the objective is to characterize the patients both clinically and biologically, histologically and genomically. The clinical and biological characterizations will allow us to confirm that our cohort is comparable with data from the literature. The complement of immunohistochemical and molecular analyses will provide more details on the differences between long-term patients responding to treatment and refractory patients.
CONDITIONS
Official Title
Identification of Genetic, Phenotypic, Clinical, Biological and Histological Factors Differentiating Patients With Ovarian Cancer Who Are Refractory to Platinum-based Therapy From Patients Defined as Long-term Responders to Platinum-based Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients treated at the Jean Perrin Center with ovarian cancer at any stage
- Treated with platinum-based chemotherapy as first-line treatment
- Belong to one of two groups: refractory (progressed during first-line treatment) or long-term responders (no progression 5 years after treatment)
- Affiliated with a social security scheme
- Signed genetic consent form
You will not qualify if you...
- Patients under 18 years old
- Pregnant patients
- Patients under guardianship or conservatorship
- Patients who refuse collection of medical or paramedical data
- Patients without available biological material for genomic analysis (FFPE block)
- Patients under administrative, judicial decision, or State Medical Aid (AME)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Centre Jean Perrin
Clermont-Ferrand, PUY DE DOME, France, 63001
Actively Recruiting
Research Team
J
Judith PASSILDAS JAHANMOHAN, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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