Actively Recruiting
Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance
Led by University of Michigan · Updated on 2025-09-03
3200
Participants Needed
1
Research Sites
904 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Investigational Weight Management Clinic now entitled the Weight Management Program at the University of Michigan was created to identify strategies that will result in cost-effective, long term weight management for overweight and obese individuals. The driving hypothesis of the clinic is that the 'one size fits all' philosophy is untenable with a complex disease such as obesity. The clinic will serve as a portal for patients to choose standard clinical care or to explore alternatives from a variety of clinical studies offered through the clinic. These studies will include further investigations into nutrition, the biological basis of weight and weight management and protocols using approved and experimental pharmaceuticals as well as technologies that aid in self-management of weight.
CONDITIONS
Official Title
Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Obese males and females aged over 20 years with a BMI of 27 kg/m2 or higher
- Lean individuals with BMI between 17 and 27 kg/m2
- Able and willing to provide written informed consent for the trial
You will not qualify if you...
- Inherited disorders of lipid metabolism
- History of cancer within the last 5 years
- HIV antibody positive
- Solid organ transplant recipients
- Participation in any other clinical trial within 90 days before this trial
- Pregnant or lactating females
- Uncontrolled thyroid disease
- Unstable angina or New York Heart Association class II heart failure or above
- Gastrointestinal motility disorders
- Unstable neuropsychiatric diseases including major depression, anxiety, or eating disorders such as binge eating, bulimia, or anorexia
- End stage kidney or liver disease
- Autoimmune disorders such as systemic lupus erythematosus
- Body weight changes exceeding 5 kg in the previous 3 months
- Prior bariatric surgery
- History or current alcohol or substance abuse, or recent changes in smoking habits
- Women of childbearing age must use reliable contraception
- Any other medical condition that could interfere with participation or completion of the study
- Unwilling or unable to consent for the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48106
Actively Recruiting
Research Team
A
Amy E Rothberg, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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