Study to Identify Who Benefits From Platelet-Rich Plasma PRP Injections for Chronic Tennis Elbow

What this Trial Is About

Researchers are studying adults with chronic lateral epicondylalgia, also known as tennis elbow, to understand how patients respond to platelet-rich plasma PRP injections. This observational study aims to find out how many patients show improvement 90 days after receiving PRP treatment and to explore clinical, demographic, and work-related factors linked to treatment response. The study also seeks to develop a model that can predict which patients are likely to benefit from PRP. Participants will have already received a PRP injection within the past 48 hours before joining the study. They will attend three visits at the start Day 0, Day 45, and Day 90. During these visits, they will undergo clinical exams, pain assessments using scales like EVA and DN4, hand grip strength tests, and complete questionnaires such as the PRTEE. The Clinical Global Impression - Change CGI-C scale will be used at Days 45 and 90 to evaluate how they respond to treatment. Most procedures are part of routine care except for the additional CGI-C assessments. Throughout the approximately three-month follow-up, researchers will collect information on participants professional activities, medical history, and treatments. They will monitor pain levels, hand strength, and functional abilities over time. The main outcome measure is treatment response at 90 days post-injection. Secondary outcomes include identifying factors predicting response and tracking changes in clinical and functional status from baseline to Day 90.

Identification of Responders to Platelet-Rich Plasma (PRP) Injections in Lateral Elbow Epicondylalgia