Actively Recruiting

Age: 18Years +
All Genders
NCT07496983

Identification of Responders to Platelet-Rich Plasma (PRP) Injections in Lateral Elbow Epicondylalgia

Led by Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape · Updated on 2026-03-27

139

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this non-interventional study is to identify patients who respond to platelet-rich plasma (PRP) injections for chronic lateral epicondylalgia (tennis elbow) and to investigate factors associated with treatment response. The study will include approximately 139 adults (18 years and older) with chronic lateral elbow pain who received a PRP injection within the last 48 hours. The main question it aims to answer is: How many patients respond to PRP treatment for chronic lateral epicondylalgia at 90 days after injection? Secondary questions include: Which clinical, demographic, and occupational factors are associated with response to PRP? Can a predictive model be developed to identify patients likely to respond to PRP? How do pain, hand grip strength, and functional outcomes evolve over 90 days in responders versus non-responders? Participants will: Attend three visits at baseline (Day 0), Day 45, and Day 90. Undergo clinical examinations, pain assessments (EVA, DN4), functional tests (hand grip, PRTEE), and questionnaires. Have data on professional activities, medical history, and treatments collected. All procedures are part of routine care, except for the addition of the Clinical Global Impression - Change (CGI-C) scale at Day 45 and Day 90 to assess treatment response. The study will be conducted at the CMRRF de Kerpape and the CHU de Rennes in France. Each participant will be followed for approximately 3 months.

CONDITIONS

Official Title

Identification of Responders to Platelet-Rich Plasma (PRP) Injections in Lateral Elbow Epicondylalgia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Chronic lateral epicondylalgia (tennis elbow) diagnosed clinically or by imaging (ultrasound or MRI) lasting more than 3 months
  • Received a platelet-rich plasma (PRP) injection within the last 48 hours
  • Medically stable
  • Able to provide informed consent or non-opposition
  • Affiliated with a social security system
Not Eligible

You will not qualify if you...

  • Received PRP injection more than 48 hours before inclusion
  • Participation in another clinical study with an exclusion period
  • Adults under legal protection
  • Pregnant women

AI-Screening

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Trial Site Locations

Total: 1 location

1

Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles (CMRRF) de Kerpape

Ploemeur, France, 56270

Actively Recruiting

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Research Team

T

Thomas Julienne, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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