Actively Recruiting

Age: 18Years +
All Genders
NCT00568490

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

Led by Stanford University · Updated on 2025-07-02

200

Participants Needed

1

Research Sites

1443 weeks

Total Duration

On this page

Sponsors

S

Stanford University

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to identify and confirm new blood and tissue markers for prognosis and tumor hypoxia. Tumor hypoxia, or the condition of low oxygen in the tumor, has been shown to increase the risk of tumor spread and enhance tumor resistance to the standard treatment of radiation and chemotherapy in head and neck and lung cancers. We have recently identified several proteins or markers in the blood and in tumors (including osteopontin, lysyl oxidase, macrophage inhibiting factor and proteomic technology) in the laboratory that may be able to identify tumors with low oxygen levels or more aggressive behaving tumors.

CONDITIONS

Official Title

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed squamous cell carcinoma of the head and neck sites or non-small cell lung cancer, or relatives of patients with histologically confirmed squamous cell carcinoma of the head and neck.
  • Able to sign a Stanford IRB approved consent form
Not Eligible

You will not qualify if you...

  • Refuse or unable to sign an IRB approved consent form.
  • Refuse to be contacted in the future for follow up.

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Trial Site Locations

Total: 1 location

1

Stanford University School of Medicine

Stanford, California, United States, 94305

Actively Recruiting

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Research Team

E

Eyiwunmi Laseinde

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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