Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT02677064

Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute Leukemia

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-01-20

1365

Participants Needed

3

Research Sites

574 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators are doing this research study to assess the percentage of patients receiving stem cell transplantation for the type of blood cancer you have. They want to know how many patients get a transplant and why some patients do get a transplant while others do not. Also they want to explore why some patients elect not to undergo stem cell transplantation, when it is recommended by their physicians.

CONDITIONS

Official Title

Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute Leukemia

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with newly diagnosed or relapsed acute leukemia, including those undergoing reinduction due to primary induction failure
  • Patients diagnosed with MDS, MPN, or MDS/MPN overlap who meet criteria such as significant cytopenia, bone marrow blasts over 5%, disease progression, or specific risk scores
  • Patients with myelofibrosis meeting low risk or higher DIPSS criteria with anemia, circulating blasts, or adverse cytogenetics
  • Patients with acute leukemia or MDS/MPN who relapse after first allografts
  • Patients aged 18 to 80 years
  • Relapse defined as re-emergence of abnormal myeloid blasts of 5% or more or any relapse prompting treatment intervention
Not Eligible

You will not qualify if you...

  • Patients diagnosed with polycythemia vera (PV)
  • Patients diagnosed with essential thrombocytosis (ET)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Hartford Healthcare Cancer Institute @ Hartford Hospital

Hartford, Connecticut, United States, 06102

Actively Recruiting

2

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

3

Lehigh Valley Health Network

Allentown, Pennsylvania, United States, 18103

Active, Not Recruiting

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Research Team

R

Roni Tamari, MD

CONTACT

S

Sergio Giralt, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute Leukemia | DecenTrialz