Actively Recruiting
To Identify Potential New Urine Markers for the Screening of Prostate Cancer
Led by Chinese University of Hong Kong · Updated on 2025-05-06
10000
Participants Needed
1
Research Sites
363 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prostate gland is a clinically important male sexual organ and its main function is for the production of semen. Globally, it is the second most common cancer in men globally and is also the fifth cancer cause for death in male. Despite the improvement in the understanding of prostate cancer, the current usage of serum prostate specific antigen (PSA) as a diagnostic marker is still not ideal. Many patients with elevated PSA and then subjected to prostate biopsy were found to have no prostate cancer. Therefore, there is a need to discover new biological markers to improve the current situation in diagnosis and also management of prostate cancer. From the earlier small-scale studies, urinary spermine levels have been shown to correlate well with prostate cancer diagnosis and cancer aggressiveness. Due to its nature, it could provide a more convenient and non-invasive method for detecting prostate cancer. The purpose of this study was to collect urine samples to study the role of potential new urine diagnostic markers (including Spermine and others) for prostate cancer diagnosis.
CONDITIONS
Official Title
To Identify Potential New Urine Markers for the Screening of Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult male patients aged over 18 years
- Serum PSA level above 4 ng/ml
- Clinically planned for prostate biopsy
You will not qualify if you...
- Recent urinary tract infection within 6 weeks before PSA testing and urine collection
- Recent urethral procedures such as Foley catheter insertion or cystoscopy within 6 weeks before PSA testing and urine collection
- Use of 5 alpha reductase inhibitors in the past 6 months
- No history of surgery for prostate conditions
- Refusal or inability to provide consent for the study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Prince of Wales Hospital
Shatin, Hong Kong
Actively Recruiting
Research Team
C
Chi Fai Ng, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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