Actively Recruiting
Identifying and Caring for Individuals With Inherited Cancer Syndrome
Led by OHSU Knight Cancer Institute · Updated on 2026-01-23
27500
Participants Needed
2
Research Sites
316 weeks
Total Duration
On this page
Sponsors
O
OHSU Knight Cancer Institute
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and ovarian cancer or Lynch syndromes) instead of only testing people whose families are known to be high risk.
CONDITIONS
Official Title
Identifying and Caring for Individuals With Inherited Cancer Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All participants must be 18 years of age or older
- Retrospective Cohort A: Patients may or may not have cancer diagnosis
- Retrospective Cohort A: Patients have received genetic counseling in the past 5 years
- Retrospective Cohort A: Patients have genetic variants including BRCA1, BRCA2, and/or Lynch syndrome
- Cohort A: Patients have received genetic counseling in the past 1 to 2 years
- Cohort A: Includes patients with BRCA1, BRCA2, and/or Lynch syndrome genetic variants
- Cohort B: Must create a secure Healthy Oregon Project app account
- Cohort B: Must provide consent to the project and the HOP repository
- Cohort B: Must choose to submit a DNA sample
- Cohort B: Patients diagnosed with any National Cancer Institute (NCI)-reportable cancers including ductal carcinoma in situ and/or in situ breast cancer
- Cohort B: Must have had a medical encounter within the past 12 months
- Cohort B: Excludes Cohort A participants
- Cohort C: Must create a secure Healthy Oregon Project app account
- Cohort C: Must provide consent to the project and the HOP repository
- Cohort C: Must choose to submit a DNA sample
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Providence Portland Medical Center
Portland, Oregon, United States, 97213
Actively Recruiting
2
OHSU Knight Cancer Institute
Portland, Oregon, United States, 97239
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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