Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05787795

Identifying and Characterizing Preclinical MS

Led by Yale University · Updated on 2025-11-14

1000

Participants Needed

1

Research Sites

575 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

R

Roche-Genentech

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.

CONDITIONS

Official Title

Identifying and Characterizing Preclinical MS

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older
  • Having at least one risk factor for multiple sclerosis, including:
    • Radiologically isolated syndrome
    • Family history of multiple sclerosis in a first-degree relative
    • Personal risk factors such as smoking, obesity, Epstein Barr virus infection, Vitamin D deficiency, or genetic risk score
Not Eligible

You will not qualify if you...

  • Currently pregnant
  • Diagnosis of multiple sclerosis or any ongoing systemic autoimmune disease
  • Currently receiving treatment with immunosuppressive medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Yale University

North Haven, Connecticut, United States, 06473

Actively Recruiting

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Research Team

E

Erin Longbrake, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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