Actively Recruiting
Identifying Genetic Targets in Gynecological Tumors
Led by Azienda USL Reggio Emilia - IRCCS · Updated on 2025-09-11
180
Participants Needed
1
Research Sites
310 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to identfy genetic targets involved in the pathogenesis of gynecological tumors, with a focus on high-grade serous ovarian carcinoma. Using a triple approach - in silico, ex vivo and in vitro - the study will investigate the role of gonadotropins and their related signaling pathways in the epithelial ovarian cancers. Gene and protein expression levels will be evaluated through transcriptomic analysis, immunohistochemistry and functional assays on tumor cell lines. The goal is to uncover potential diagnostic or therapeutic targets in gynecological malignancies.
CONDITIONS
Official Title
Identifying Genetic Targets in Gynecological Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult women 65 18 years old
- Histologically confirmed diagnosis of epithelial ovarian cancer (including high-grade serous, endometrioid, mucinous, clear cell, or mesonephric-like histotypes)
- Signed informed consent (for prospective cases) or ethically approved waiver (for retrospective samples)
You will not qualify if you...
- Refusal to sign informed consent
- Diagnosis of low-grade or non-epithelial ovarian tumors
- Patients whose clinical or pathological data are unavailable or insufficient for study inclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Azienda USL IRCCS di Reggio Emilia
Reggio Emilia, Italy
Actively Recruiting
Research Team
B
Beatrice Melli, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here