Actively Recruiting

Phase 2
Age: 45Years +
FEMALE
NCT06092892

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

Led by Alice Chung · Updated on 2026-05-11

45

Participants Needed

3

Research Sites

364 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy proven image detected nodal disease treated with upfront lumpectomy or mastectomy with TAD followed by adjuvant therapy. This is a prospective, single arm phase II clinical trial. Patients will be screened and enrolled per eligibility criteria. Patient, tumor, and treatment data will be documented.

CONDITIONS

Official Title

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

Who Can Participate

Age: 45Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women age 65
  • Clinical T1-2N0 ER+ invasive breast cancer
  • Ultrasound detected biopsy proven axillary nodal disease
  • Written informed consent and ability to comply with study requirements
Not Eligible

You will not qualify if you...

  • Palpable nodes on physical exam
  • Her2+ or ER- invasive breast cancer
  • Extranodal extension greater than 3 mm on nodal biopsy
  • More than 2 suspicious nodes on preoperative imaging

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute

Los Angeles, California, United States, 90048

Actively Recruiting

2

CS Cancer at Huntington Cancer Center

Pasadena, California, United States, 91105

Actively Recruiting

3

CS Cancer at Valley Oncology Medical Group

Tarzana, California, United States, 91356

Actively Recruiting

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Research Team

C

Clinical Trial Navigator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases | DecenTrialz