Actively Recruiting
Imaging of Endolymphatic Hydrops at 7T MRI
Led by King's College Hospital NHS Trust · Updated on 2024-03-06
16
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
K
King's College Hospital NHS Trust
Lead Sponsor
K
King's College London
Collaborating Sponsor
AI-Summary
What this Trial Is About
Imaging endolymphatic hydrops with 7T Sodium Imaging and 1.5 T gadolinium enhanced imaging: a comparison of diagnostic outcomes with 3T MRI Duration of study 24 months Study design Prospective cohort study Number of patients 16 patients 1. To evaluate whether imaging both 1.5T and 3T have an equivalent performance in terms of diagnosing MD ears with delayed post gadolinium enhanced MRI (applying quantitative and semi-quantitative analysis) 2. To compare the diagnostic performance of Sodium Imaging at 7T (applying semi-quantitative analysis) with that of delayed post gadolinium enhanced 3T MRI in distinguishing symptomatic from asymptomatic Meniere's Disease (MD) ears.
CONDITIONS
Official Title
Imaging of Endolymphatic Hydrops at 7T MRI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female, 18 years of age or older
- Ability to understand patient information and provide written informed consent
- Unilateral audio-vestibular symptoms meeting 2015 Barany criteria for unilateral Meniere's Disease of less than 5 years duration
- Scheduled for clinical MRI scanning to confirm Meniere's Disease diagnosis as part of standard care
You will not qualify if you...
- Standard contraindications to 7T MRI
- Known allergy to gadolinium contrast
- Calculated glomerular filtration rate (GFR) less than 30 ml/min
- Previous temporal bone surgery or trauma
- Other known temporal bone pathology
- Need for early post gadolinium sequences (e.g., autoimmune inner ear disease)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
King's College London
London, United Kingdom, SW1P 4AL
Actively Recruiting
Research Team
S
Stephen EJ Connor, MRCP FRCR
CONTACT
I
Irumee Pai, FRCS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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