Actively Recruiting
Imaging Features for the Risks for Recurrence After Stereotactic Radiosurgery in Brain Metastasis
Led by Asan Medical Center · Updated on 2024-05-14
132
Participants Needed
1
Research Sites
138 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This trial uses multi-parametric magnetic resonance imaging (MRI) to develop and validate imaging risk score to predict radiation necrosis in participants with brain metastasis treated with radiation therapy. Diagnostic procedures, such as multi-parametric magnetic resonance imaging (MRI), may improve the ability to diagnose radiation necrosis early and help establish treatment strategies.
CONDITIONS
Official Title
Imaging Features for the Risks for Recurrence After Stereotactic Radiosurgery in Brain Metastasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who underwent stereotactic radiosurgery (SRS, gamma-knife radiosurgery or cyberknife radiosurgery) for brain metastases
- Patients with one to ten newly diagnosed brain metastases
- Patients without acute neurological symptoms
- Karnofsky performance status score of 70 or higher
- Brain MRI performed within 1 month of enrollment
- Measurable enhancing brain lesions on MRI
- Available reference standard such as second-look surgery or follow-up imaging for clinic-radiologic assessment
- Longest tumor diameter greater than 1.5 cm for tumor habitat analysis
You will not qualify if you...
- Prior brain surgery, stereotactic radiosurgery, or whole-brain radiation therapy
- Diagnosis of leukemia, lymphoma, germ-cell tumor, small-cell lung cancer, leptomeningeal disease, or unknown primary tumor
- Age under 18 years
- Lack of baseline MRI
- Nonmeasurable enhancing lesions on MRI, including lesions smaller than 10 mm, lesions with borders that cannot be reliably measured, dural metastases, bony skull metastases, and leptomeningeal disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Asan Medical Center
Seoul, South Korea
Actively Recruiting
Research Team
H
Ho Sung Kim, MD, PhD
CONTACT
J
Ji Eun Park, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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