Actively Recruiting
Imaging Retinal Vasculature in Infant Eyes
Led by Duke University · Updated on 2025-10-06
16
Participants Needed
2
Research Sites
151 weeks
Total Duration
On this page
Sponsors
D
Duke University
Lead Sponsor
U
University of Pennsylvania
Collaborating Sponsor
AI-Summary
What this Trial Is About
Retinopathy of prematurity is a leading cause of childhood blindness worldwide. The fovea, a critical location in the retina determining visual acuity and visual function, and the blood vessels around it, are abnormally developed in infants with retinopathy of prematurity. However, how these blood vessels form during development of the human fovea remains unclear. This research will advance our understanding of the fundamental knowledge of how the blood vessels around the fovea form in infants, and how they change in diseased states such as preterm birth or retinopathy of prematurity.
CONDITIONS
Official Title
Imaging Retinal Vasculature in Infant Eyes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthcare provider agrees that study personnel may contact the parent or legal guardian
- Parent or legal guardian is willing and able to consent for the infant's participation
- Infant meets American Academy of Pediatrics guidelines for ROP screening and is less than 34 weeks 6 days postmenstrual age at first visit
You will not qualify if you...
- Parent or legal guardian is unwilling or unable to provide consent
- Infant has eye conditions preventing retinal imaging (e.g., corneal opacity or cataract)
- Infant has other health conditions severely impacting brain development (e.g., anencephaly)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Duke University
Durham, North Carolina, United States, 27710
Actively Recruiting
2
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Not Yet Recruiting
Research Team
X
Xi Chen, MD
CONTACT
M
Michelle N McCall
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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