Actively Recruiting
The Immediate Effect of Applying Transcutaneous Electrical Nerve Stimulation (TENS) on Sympathetic Ganglion and Gastrocnemius for Popliteal Blood Flow
Led by Kaohsiung Medical University · Updated on 2025-07-18
43
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the immediate hemodynamic effects of transcutaneous electrical nerve stimulation (TENS) on the popliteal artery and vein. Vascular issues like PAOD and DVT are common in patients with diabetes, obesity, or immobility due to increased resistance and reduced blood flow. Traditional treatments (medication or surgery) are not always feasible, prompting interest in TENS as an alternative. Although primarily used for pain relief, TENS may enhance blood flow. This research compares different stimulation frequencies (80 Hz vs. 4 Hz) and sites (gastrocnemius muscle vs. thoracolumbar sympathetic ganglia) to identify the most effective configuration.
CONDITIONS
Official Title
The Immediate Effect of Applying Transcutaneous Electrical Nerve Stimulation (TENS) on Sympathetic Ganglion and Gastrocnemius for Popliteal Blood Flow
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy people
- Age: 18 years and above (inclusive)
- Body mass index (BMI) between 18.5 and 24
You will not qualify if you...
- Unable to complete two interventions within a week
- Have contraindications to electrotherapy (for example: metal implants in the body, open wounds, pregnancy, sensory loss)
- Obvious varicose veins 4. Unable to lie down for about 1 to 2 hours 5. Taking drugs or nutritional supplements that affect autonomic nervous activity or vasodilation (for example: Ginkgo biloba) 6. Smoking 7. Ankle and Ankle Index (ABI) less than 0.9 or greater than 1.3
AI-Screening
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Trial Site Locations
Total: 1 location
1
Kaohsiung Medical University
Kaohsiung City, Taiwan, Taiwan, 807378
Actively Recruiting
Research Team
M
Mengjie Shen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
4
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