Study of Different Reconstruction Methods After Proximal Gastrectomy for Gastric and Esophagogastric Junction Cancer Evaluating Immediate and Long-Term Functional Outcomes and Quality of Life

What this Trial Is About

Proximal gastric and esophagogastric junction cancers make up about 40% of all stomach cancers. This research focuses on patients with localized tumors who undergo proximal gastrectomy, a surgery removing the upper stomach and part of the esophagus. The study aims to compare different ways to reconstruct the digestive tract after surgery and understand how these affect patient quality of life, symptoms like reflux, food passage, and nutritional status, which are often overlooked in favor of cancer survival outcomes. The study observes patients who have had proximal gastrectomy using various reconstruction techniques such as direct esophagogastrostomy, double-tract reconstruction, jejunal interposition, and newer anti-reflux surgeries. It tracks patients treated by open, laparoscopic, or robotic surgery from January 2025 to December 2026. Patients are grouped based on whether they experience any complications after surgery to assess how reconstruction methods influence these outcomes. Participants will be monitored for up to one year after surgery with evaluations including complications within 90 days, survival, tumor progression, and local recurrence. Functional outcomes like reflux esophagitis, anastomotic stricture, dumping syndrome, body weight, hemoglobin levels, and food passage will be assessed at 6 and 12 months. This comprehensive follow-up aims to provide detailed information on the immediate and long-term effects of different reconstruction methods on patients health and quality of life.

Immediate and Functional Results of Different Types of Reconstructions After Proximal Gastrectomy For Gastric and Esophagogastric Junction Cancer