Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06899529

Immediate Postoperative Bevacizumab Administration in Proliferative Diabetic Retinopathy Patients Undergoing Vitrectomy

Led by Christian Ophthalmic Surgery Expedition Network · Updated on 2025-03-28

150

Participants Needed

1

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients undergoing surgery for complications related to diabetes will be recruited.

CONDITIONS

Official Title

Immediate Postoperative Bevacizumab Administration in Proliferative Diabetic Retinopathy Patients Undergoing Vitrectomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject age is > 18
  • Subject consents to study participation and can complete 6 months of follow-up
  • Type I or II Diabetes Mellitus with active Proliferative Diabetic Retinopathy in the study eye
  • Best-corrected visual acuity in the study eye ranges from 20/40 to Hand Motions
  • Need for pars plana vitrectomy due to non-clearing vitreous hemorrhage (present at least 3 months), threatening or fovea-involving tractional retinal detachment, or extensive fibrovascular proliferation (>3 clock hours) threatening or involving the fovea
  • Only one eye per patient is eligible for the study
Not Eligible

You will not qualify if you...

  • Significant retinal or optic nerve disease unrelated to diabetes causing two or more lines of vision loss in the study eye (e.g., macular degeneration, optic neuritis, glaucoma, amblyopia)
  • Significant corneal opacity causing two or more lines of vision loss in the study eye (e.g., corneal scar, ectasia)
  • Previous vitrectomy surgery in the study eye
  • Uncontrolled neovascular glaucoma with intraocular pressure > 30 mmHg despite treatment in the study eye
  • Uncontrolled hypertension with systolic > 200 mmHg or diastolic > 120 mmHg despite multiple medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sky Vision

Querétaro City, Querétaro, Mexico, 76165

Actively Recruiting

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Research Team

R

Ryan Rush, MD

CONTACT

C

Christi Rush

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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