Actively Recruiting

Phase 4
Age: 18Years - 80Years
All Genders
NCT05838365

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

Led by University of Milan · Updated on 2023-05-01

220

Participants Needed

1

Research Sites

339 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main aim of the present study is to investigate implant success rate after 5 years of function of immediate (Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement) loading of two-pieces zirconia implant, placed in pristine bone without bone regeneration. Implant success rate will be defined according to Buser's criteria. Secondary endpoints: Marginal bone level (MBL) evaluation by means of standardized radiographs; Clinical evaluation of biological (e.g. Plaque Index, PI; Probing Pocket Depth, PPD, Bleeding on Probing, BOP; suppuration upon probing/palpation) and prosthetic/technical complications; Clinical evaluation of soft tissue width, keratinized tissue, marginal and interproximal soft tissue recession; Patient reported outcome measures (PROMs) by questionnaire administration:

CONDITIONS

Official Title

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Sistemically healthy patients
  • Partial edentulism
  • Premolar position for implant placement
  • Molar position for implant placement
  • Bone width of at least 6 mm and height of at least 10 mm at implant site
  • At least 1 mm of keratinized tissue at implant site
  • Full understanding of surgical treatments and study schedule
  • Ability to comprehend and sign informed consent form
Not Eligible

You will not qualify if you...

  • Smoking more than 10 cigarettes a day
  • Serious kidney or liver diseases
  • Uncontrolled diabetes
  • Taking bisphosphonates
  • History of radiotherapy to head and neck
  • Current antiblastic chemotherapy
  • Congenital or acquired immunodeficiency
  • Pregnancy
  • Connective tissue disorders
  • Untreated stage III or IV periodontitis
  • Autoimmune diseases
  • Oral parafunctions

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

San Paolo Hospital

Milan, Italy

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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