Alveolar Ridge Preservation With Immediate or Late Implant Placement: a Multicenter Randomized Controlled Trial

What this Trial Is About

Researchers are evaluating the effects of immediate versus delayed implant placement in patients needing a single implant in the front upper jaw (premaxilla). This multicenter randomized controlled trial involves 60 patients across six centers, aiming to compare the need for soft tissue grafting after alveolar ridge preservation between these two approaches. The trial also collects data on hard and soft tissue changes, clinical outcomes, aesthetics, and patient and clinician feedback over several years. Participants undergo digital planning and have a tooth-supported surgical guide made before tooth extraction. In the control group, ridge preservation is done after tooth extraction, followed by implant placement four months later. In the test group, the implant is placed immediately after extraction and ridge preservation is done by filling the gap around the implant. Both groups receive a provisional crown on the day of implant surgery, replaced with a permanent one three months later. Soft tissue grafting is assessed and possibly performed six months after extraction based on specific clinical criteria. During the study, participants receive preoperative antibiotics and anti-inflammatory medications, and detailed assessments including CBCT scans, clinical photos, and 3D digital models are used to evaluate tissue changes and implant outcomes. A panel of clinicians reviews the need for soft tissue augmentation at six months. Follow-up visits and evaluations continue up to five years to measure implant survival, tissue changes, aesthetic outcomes, and complications. The trial includes careful monitoring and blinded assessment to ensure unbiased results.

Immediate Versus Late Placement