Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
Healthy Volunteers
NCT04416191

Immune Cells During Disuse and Recovery

Led by University of Utah · Updated on 2025-12-05

45

Participants Needed

1

Research Sites

311 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an interventional study enrolling healthy individuals aged 18-35 and 60-85 to understand the recovery of muscle health following a period of inactivity. The enrollment goal is 45 participants. The study will occur over the course of 1-2 months where participants will undergo testing before and after a 2-week limb immobilization period.

CONDITIONS

Official Title

Immune Cells During Disuse and Recovery

Who Can Participate

Age: 18Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18-35 and 60-85 years
  • Ability to sign informed consent
  • Living independently prior to admission
Not Eligible

You will not qualify if you...

  • History of cardiovascular disease such as congestive heart failure, coronary artery disease, or right-to-left shunt
  • History of endocrine or metabolic diseases including hypo/hyperthyroidism and diabetes
  • History of kidney disease or failure
  • Vascular disease or risk of deep vein thrombosis including family history of thrombophilia or related conditions
  • Use of anticoagulant therapy like Coumadin or heparin
  • Elevated blood pressure with systolic over 150 or diastolic over 100
  • Presence of implanted electronic devices such as pacemakers or stimulators
  • Cancer or cancer treatment within the past year except basal cell carcinoma
  • Current weight-loss diet
  • Chronic systemic corticosteroid use for two or more weeks within four weeks before enrollment and during study
  • Use of androgens or growth hormone within six months before enrollment and during study
  • History of stroke with motor disability
  • Recent gastrointestinal bleeding within the past 12 months
  • History of liver disease
  • History of respiratory disease including acute upper respiratory infection or chronic lung disease
  • Pregnancy confirmed by a test
  • Employment as staff reporting directly or indirectly to an investigator
  • Any other condition deemed exclusionary by the principal investigator or faculty physician

AI-Screening

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Trial Site Locations

Total: 1 location

1

The University of Utah

Salt Lake City, Utah, United States, 84112

Actively Recruiting

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Research Team

M

Micah Drummond, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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