Actively Recruiting
Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons
Led by Odense University Hospital · Updated on 2025-12-05
30
Participants Needed
2
Research Sites
501 weeks
Total Duration
On this page
Sponsors
O
Odense University Hospital
Lead Sponsor
U
University of Southern Denmark
Collaborating Sponsor
AI-Summary
What this Trial Is About
Tendon pathologies (enthesitis) are a characteristic component of psoriatic arthritis (PsA), and are observed in 35% to 50% of PsA patients. The Achilles tendon is one of the most commonly affected sites. This condition often causes great morbidity and loss of quality of life, and response only suboptimal to current intervention strategies. One of the main obstacles for the development of effective treatment methods is that the disease mechanisms remain poorly understood. To our knowledge, no one has yet ascertained the presence and function of immune-competent cells and inflammatory markers in tendons tissue from PsA patients suffering from Achilles enthesitis.
CONDITIONS
Official Title
Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fulfilling the CASPAR criteria for psoriatic arthritis
- Insertional Achilles tendon pain
- Ultrasound evidence of inflammatory disease at the painful Achilles tendon insertion, defined as abnormally hypoechoic or thickened tendon at the bony attachment seen in two planes, possibly with Doppler signal or bony changes including enthesophytes and erosions
You will not qualify if you...
- Having other inflammatory rheumatic diseases besides psoriatic arthritis
- Ultrasound signs of complete rupture of the Achilles tendon
- Not wishing to participate or not suitable for project evaluation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Odense University Hospital
Odense, Denmark, 5000
Actively Recruiting
2
Diagnostic Center
Silkeborg, Denmark
Actively Recruiting
Research Team
M
Maja S. Kragsnaes, MD PhDfellow
CONTACT
T
Torkell J. Ellingsen, Prof MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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