Actively Recruiting
Immune Function and the Progression to T1D
Led by University of Florida · Updated on 2026-04-09
2800
Participants Needed
3
Research Sites
4174 weeks
Total Duration
On this page
Sponsors
U
University of Florida
Lead Sponsor
J
Juvenile Diabetes Research Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.
CONDITIONS
Official Title
Immune Function and the Progression to T1D
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to have blood drawn
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Kieran McGrail
Gainesville, Florida, United States, 32610
Actively Recruiting
2
The Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
3
Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
J
Jennifer L Hosford, MPH
CONTACT
K
Kieran McGrail
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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