Actively Recruiting

Age: 18Years +
All Genders
NCT06116032

Immune Profiling for Cancer Immunotherapy Response

Led by Dartmouth-Hitchcock Medical Center · Updated on 2025-12-16

1500

Participants Needed

1

Research Sites

326 weeks

Total Duration

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AI-Summary

What this Trial Is About

In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylation profiling across cancer types, and 2) immune-methylation profiling and cytokine profiling within cancer types.

CONDITIONS

Official Title

Immune Profiling for Cancer Immunotherapy Response

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Cancer patients receiving or will receive immunotherapy under FDA-approved indication (e.g., checkpoint inhibitor therapy with pembrolizumab, nivolumab, or ipilimumab, or cellular immunotherapy)
  • Participants are eligible regardless of the type of prior therapy, including prior immunotherapy treatments
Not Eligible

You will not qualify if you...

  • Pregnant women, fetuses, or neonates
  • Prisoners
  • Individuals with impaired decision-making capacity

AI-Screening

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Trial Site Locations

Total: 1 location

1

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03756

Actively Recruiting

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Research Team

B

Brock C Christensen, PhD

CONTACT

H

Hannah G Stolrow, BA

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Immune Profiling for Cancer Immunotherapy Response | DecenTrialz