Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT02129543

Immune Reconstitution in Stem Cell Transplant Recipients

Led by University of Miami · Updated on 2026-01-05

700

Participants Needed

1

Research Sites

747 weeks

Total Duration

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AI-Summary

What this Trial Is About

This specimen collection lab protocol will allow the investigators to prospectively study immune reconstitution in patients being treated for hematologic disorders and immune factors affecting graft versus host disease in stem-cell transplant (SCT) patients.

CONDITIONS

Official Title

Immune Reconstitution in Stem Cell Transplant Recipients

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Patients presenting to the Division of Hematology or Transplantation and Cellular Therapy, including those with various hematologic malignancies and bone marrow failure
  • Stem cell transplant donors cleared for donation and generally healthy
  • Patients planned for or receiving stem cell transplant or cellular therapy
  • Patients undergoing CAR T cell therapy including treatments with CARs, T-cell receptor transgenic cells, tumor-infiltrating lymphocytes, or donor lymphocyte infusion
  • Ability to provide blood, cerebrospinal fluid, bone marrow, or serum samples
Not Eligible

You will not qualify if you...

  • Pregnancy for patients undergoing CAR T therapy
  • No other exclusion criteria for patients in Arms A, B, and D

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Miami

Miami, Florida, United States, 33136

Actively Recruiting

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Research Team

J

Jay Spiegel, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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Immune Reconstitution in Stem Cell Transplant Recipients | DecenTrialz