Actively Recruiting

Phase Not Applicable
Age: 20Years - 36Years
All Genders
Healthy Volunteers
NCT04970836

The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort

Led by National Taiwan University Hospital · Updated on 2025-03-20

240

Participants Needed

1

Research Sites

334 weeks

Total Duration

On this page

Sponsors

N

National Taiwan University Hospital

Lead Sponsor

A

Academia Sinica, Taiwan

Collaborating Sponsor

AI-Summary

What this Trial Is About

This prospective cohort study aims to provide the evidence-based clinical guide to help decide the revaccination doses of hepatitis B vaccine that the high-risk young adults without hepatitis B seroprotective antibodies (anti-HBs titer\<10 mIU/mL) need to take.

CONDITIONS

Official Title

The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort

Who Can Participate

Age: 20Years - 36Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 20 years and born after 1987
  • Born in Taiwan and completed at least three doses of hepatitis B vaccine in infancy
  • Tested negative for hepatitis B surface antibody and surface antigen at baseline
  • Never vaccinated against hepatitis B during childhood and adolescence by questionnaire
  • Consent to receive 1 or 2 doses of hepatitis B vaccine according to group assignment
  • In good health
Not Eligible

You will not qualify if you...

  • Allergy to hepatitis B vaccine or its components (such as yeast)
  • Vaccinated against hepatitis B during childhood or adolescence
  • Positive test for hepatitis B surface antibody or surface antigen

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Family Medicine, NTUH

Taipei, Taiwan, 100

Actively Recruiting

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Research Team

C

CHYI-FENG JAN, MD, PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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