Actively Recruiting
Immune Responses in Health Care Personnel
Led by Finnish Institute for Health and Welfare · Updated on 2025-08-20
150
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
Sponsors
F
Finnish Institute for Health and Welfare
Lead Sponsor
H
Hospital District of Helsinki and Uusimaa
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is an investigator-initiated 10 year long open cohort observational study, aiming to increase the understanding of the humoral and cellular immunological mechanisms of vaccination against influenza, including effects of repeated vaccination, the duration of protection, immunity against circulating viruses, as well as factors affecting the immunological responses and immunity against other vaccine preventable infectious diseases among health care personnel.
CONDITIONS
Official Title
Immune Responses in Health Care Personnel
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Members of health care or laboratory personnel in HUS who have decided to take the seasonal influenza vaccination through routine occupational health care
- General good health as confirmed by the participant or investigator
- Written informed consent provided
- Presumed ability and willingness to participate during the starting influenza season
You will not qualify if you...
- Any confirmed or suspected immunosuppressive or immunodeficient conditions, including HIV infection
- Use of immunosuppressants or immune-modifying drugs for longer than 14 days within 6 months before vaccination; oral corticosteroids at doses of 20 mg/day or more are excluded; inhaled or topical steroids are allowed
- Pregnancy or lactation
- Acute moderate or severe illness at enrollment, with or without fever
- Contraindications to influenza vaccination
- Any other condition judged by investigators to affect study participation, participant well-being, or study outcomes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Hospital District of Helsinki and Uusimaa
Helsinki, Finland
Actively Recruiting
Research Team
H
Hanna Nohynek, MD, PhD
CONTACT
M
Merit Melin, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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