Actively Recruiting

Age: 18Years - 70Years
All Genders
NCT05126160

Immune Score Based Radiomics in Nasopharyngeal Carcinoma

Led by Zhejiang Cancer Hospital · Updated on 2021-11-18

494

Participants Needed

5

Research Sites

316 weeks

Total Duration

On this page

Sponsors

Z

Zhejiang Cancer Hospital

Lead Sponsor

R

Renmin Hospital of Wuhan University

Collaborating Sponsor

AI-Summary

What this Trial Is About

In nasopharyngeal carcinoma (NPC), tumor, node and metastasis (TNM) staging system is the main tool for determining treatment strategy and assessment of prognosis. However, the prognoses of patients with the same TNM stage after similar treatment vary widely. The aim of this study is to establish an immune score based radiomic staging system for NPC.

CONDITIONS

Official Title

Immune Score Based Radiomics in Nasopharyngeal Carcinoma

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with newly histologically confirmed non-keratinizing or keratinizing carcinoma
  • ECOG Performance status of 0 to 1
  • Normal liver function tests (ALT, AST 6 2.5 times the upper limit of normal)
  • Renal function with creatinine clearance 6 60 ml/min
  • No blood disorders with WBC > 4 x 10^9/L, hemoglobin > 90 g/L, and platelet count > 100 x 10^9/L
  • Written informed consent provided
Not Eligible

You will not qualify if you...

  • Contraindications for MRI scan
  • Previous malignancy except treated carcinoma in-situ of the cervix or basal/squamous cell carcinoma of the skin
  • Prior chemotherapy or radiotherapy except for non-melanomatous skin cancers outside the intended radiotherapy area
  • Pregnant or lactating patients
  • Severe intercurrent diseases such as unstable cardiac disease, renal disease, chronic hepatitis, poorly controlled diabetes (fasting plasma glucose > 1.5 times upper limit of normal), or emotional disturbances that may affect study compliance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Renmin Hospital of Wuhan University

Wuhan, Hubei, China, 430060

Actively Recruiting

2

Ningbo First Hospital

Ningbo, Ningbo, China, 315000

Actively Recruiting

3

Ningbo Medical Center Lihuili Hospital

Ningbo, Ningbo, China, 315000

Actively Recruiting

4

The First Affiliated Hospital of Wenzhou Medical University

Wenzhou, Wenzhou, China, 325000

Actively Recruiting

5

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China, 310022

Actively Recruiting

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Research Team

X

Xiaozhong Chen

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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