Actively Recruiting
Immune Signature of Chronic Hand Eczema Unveiled by Spatial Transcriptomics and Single-Cell Proteomics
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-03-19
40
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
Sponsors
F
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead Sponsor
L
LEO Pharma
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study explores the immune landscape of chronic hand eczema using spatial transcriptomics and single-cell proteomics, offering new insights into disease mechanisms and potential therapeutic targets.
CONDITIONS
Official Title
Immune Signature of Chronic Hand Eczema Unveiled by Spatial Transcriptomics and Single-Cell Proteomics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 65 with chronic hand eczema of endogenous or exogenous origin
- Eczema on the hands for at least 3 months or with 2 or more flare-ups in the last year
- Patients with atopic dermatitis affecting the hands and other areas, involving less than 30% of body surface area
You will not qualify if you...
- Use of immunosuppressants or biologic agents affecting eczema, except short courses of systemic corticosteroids under one month
- Use of systemic corticosteroids within one month before study enrollment
- Use of topical corticosteroids or calcineurin inhibitors within one week before enrollment
- Chronic hand eczema of mixed or unclassifiable cause will not be included in data analysis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Italy, 00168
Actively Recruiting
Research Team
K
Ketty Peris, Prof
CONTACT
N
Niccolò Gori, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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