Actively Recruiting
Immune Status and Disease Control of Inflammatory Airway Diseases
Led by First Affiliated Hospital of Ningbo University · Updated on 2026-03-25
200
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to learn how the body's immune system affects disease control in people with different airway inflammatory diseases.We want to understand: 1.Whether specific immune cell patterns in the blood are linked to how severe the disease is or how well it is controlled. Participants will: 1. Answer questions about their health and symptoms. 2. Give blood samples 3. Have lung function tests and other standard check-ups. 4. share sleep study results. We will compare people with airway diseases to healthy volunteers to see how their immune systems differ.
CONDITIONS
Official Title
Immune Status and Disease Control of Inflammatory Airway Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older (40 years or older for COPD patients)
- Clinical diagnosis of asthma, ABPA, bronchiectasis, OSAS, or COPD based on established criteria
- PRISm patients with post-bronchodilator FEV1/FVC ≥70% and FEV1 <80% predicted
- Smoking controls with at least 10 pack-years history, normal lung function, and no chronic respiratory symptoms
- Healthy controls with normal lung function, FeNO <20 ppb, total IgE <100 IU/mL, no chronic disease, less than 10 pack-years smoking, and no immunosuppressant use within 3 months
You will not qualify if you...
- Severe respiratory diseases other than included ones, such as pulmonary embolism, pneumothorax, pulmonary hypertension, interstitial lung disease, or active lung cancer
- Severe systemic diseases interfering with study completion, including myocardial infarction, severe arrhythmia, liver or kidney insufficiency, blood disorders, or malignancy
- Acute exacerbation within 4 weeks before enrollment or recent systemic use of antibiotics, antifungal, immunosuppressive, cytotoxic agents, or corticosteroids (except long-term maintenance therapy)
- Pregnant or lactating women
- Poor compliance as judged by investigators
- Currently participating in other clinical studies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Ningbo University
Ningbo, Zhejiang, China
Actively Recruiting
Research Team
C
chao Cao, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
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