Actively Recruiting
ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study
Led by Western University of Health Sciences · Updated on 2025-07-17
30
Participants Needed
2
Research Sites
24 weeks
Total Duration
On this page
Sponsors
W
Western University of Health Sciences
Lead Sponsor
A
American Osteopathic Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine whether osteopathic manipulative treatment (OMT) enhances immune system readiness in healthy adults compared to exercise or sham light treatment. Specifically, the goal of this study is to assess circulating immune cells and signaling molecules in the blood in response to these various treatments. It aims to compare: Complete Blood Counts (CBC) and blood immune signaling molecule levels in healthy adults in response to OMT, sham light touch, and exercise, with measurements taken at multiple time points. Researchers will compare immune blood cells and signaling molecules in response to OMT versus sham light touch and exercise within the same group of healthy adults measured at three time points for each of the three total visits. Participants will do a 15-minute OMT session, a 15-minute light sham session, or a 15-minute exercise session at each of their three separate visits (they will do one of each over the course of their 3 appointments in random order). They will have three blood draws taken at each of those three visits. They will also fill out a Global Physical Activity Questionnaire (GPAQ) survey to assess their level of physical activity throughout the study.
CONDITIONS
Official Title
ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be 18 years of age or older
- Provide informed consent
- Be healthy with a body mass index (BMI) under 30 and have no primary or secondary immune deficiency or autoimmune disease
- Not be immunocompromised
- Not be using or recently have used immune-altering medications like corticosteroids, cyclosporin, tacrolimus, or pimecrolimus
- Have not received lymphatic OMT, acupuncture, physical therapy, chiropractic, or massage therapy in the previous 4 weeks
- Be able to receive OMT with lymphatic techniques
- Be able to tolerate 12 minutes of moderate physical activity
- Not be pregnant or breastfeeding
- Have not had a splenectomy or other spleen or cancer-related surgery within the past 6 months
- Be infection-free for 6 weeks before starting the study and have not received any immunizations in the past 6 weeks
- Be willing to avoid strenuous activity at least 24 hours before each visit
- Be willing to abstain from moderate to intense activity in the 4 hours between the 2nd and final blood draw at each visit
You will not qualify if you...
- Be younger than 18 years old
- Not provide informed consent
- Have a body mass index (BMI) over 30 or have primary or secondary immune deficiency or autoimmune disease
- Be immunocompromised
- Be using or recently have used immune-altering medications like corticosteroids, cyclosporin, tacrolimus, or pimecrolimus
- Have received lymphatic OMT, acupuncture, physical therapy, chiropractic, or massage therapy in the previous 4 weeks
- Be unable to receive OMT with lymphatic techniques
- Be unable to tolerate 12 minutes of moderate physical activity
- Be pregnant or breastfeeding
- Have had a splenectomy or other spleen or cancer-related surgery within the past 6 months
- Have had an infection in the 6 weeks before starting the study or received any immunizations in the past 6 weeks
- Not willing to avoid strenuous activity at least 24 hours before each visit
- Not willing to abstain from moderate to intense activity in the 4 hours between the 2nd and final blood draw at each visit
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Western University of Health Sciences
Pomona, California, United States, 91766
Not Yet Recruiting
2
Western University of Health Sciences
Pomona, California, United States, 91766
Actively Recruiting
Research Team
B
Brian Loveless, DO
CONTACT
E
Eric S Martinez, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
3
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