Actively Recruiting

Phase 2
Phase 3
Age: 19Years - 55Years
All Genders
Healthy Volunteers
NCT07204457

Immunogenicity and Safety of Meningococcal Conjugate Vaccine (EG-MCV4) in Healthy Adults Aged 19 to 55 Years Old

Led by EyeGene Inc. · Updated on 2025-12-01

1123

Participants Needed

1

Research Sites

84 weeks

Total Duration

On this page

Sponsors

E

EyeGene Inc.

Lead Sponsor

B

BMI Korea

Collaborating Sponsor

AI-Summary

What this Trial Is About

Phase 2/3 study to evaluate immunogenicity and safety in healthy adult participants following a single dose administration of Meningococcal (groups A, C, W-135, and Y) conjugate vaccine

CONDITIONS

Official Title

Immunogenicity and Safety of Meningococcal Conjugate Vaccine (EG-MCV4) in Healthy Adults Aged 19 to 55 Years Old

Who Can Participate

Age: 19Years - 55Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy males and females aged 19 to 55 years
  • Fully informed and voluntarily agree to participate by providing written consent
  • Available for all scheduled visits, including phone calls and in-person appointments, for the study duration
Not Eligible

You will not qualify if you...

  • History of meningococcal disease
  • Contact with infected person within 60 days before screening
  • Previous meningococcal or meningococcal antigen-containing vaccine
  • Vaccination with any other vaccine within 4 weeks before or after study vaccine
  • Fever ≥ 38°C within 3 days before screening or recent acute or chronic infections
  • History of Hepatitis B or C at screening
  • Significant acute, chronic, or progressive diseases affecting study participation
  • Malignancy or high-risk cancer within 5 years before vaccine
  • History of epilepsy, progressive neurological disease, or Guillain-Barré Syndrome
  • History of anaphylaxis or systemic urticaria within 5 years
  • Hypersensitivity to vaccine components or latex
  • Immune system affecting therapy within 6 months before screening
  • Immunodeficiency or family history of such
  • Receipt of immunoglobulin, blood products, or plasma within 90 days before screening
  • Platelet or bleeding disorders or excessive bleeding after injections
  • Current anticoagulant or new antiplatelet treatment
  • Organ or bone marrow transplantation history
  • Suspected drug or alcohol abuse within 1 year before vaccine
  • Unwillingness to use medically acceptable contraception during trial
  • Pregnant or lactating women
  • Receipt or planned receipt of investigational drug or device within 6 months before study
  • Significant abnormalities on screening tests or other investigator-determined unsuitability

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Catholic University of Eunpyeong St.Mary's Hospital

Seoul, South Korea

Actively Recruiting

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Research Team

J

Jooyoung Park

CONTACT

K

Kyung-Hee Lee

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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