Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT04615221

Immunological Mechanisms of Rejection in Uterine Transplantation

Led by Hopital Foch · Updated on 2025-09-12

30

Participants Needed

1

Research Sites

675 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study is to understand the mechanisms of rejection in uterine transplantation and to search for non-invasive markers of rejection. The biological samples necessary for our research have been or will be collected during procedures (biopsies, smears, vaginal swab, blood tests) carried out as part of the scheduled follow-up of patients. These will be samples whose collection is minimally or not invasive

CONDITIONS

Official Title

Immunological Mechanisms of Rejection in Uterine Transplantation

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient going to or having received a uterine transplant
  • Patient going to or having donated a uterus for a recipient included in the study
  • Premenopausal woman scheduled for gynecological surgery under general anesthesia
  • For 4 controls with hysterectomy, age under 45 years
  • For 6 controls without hysterectomy, age under 38 years
Not Eligible

You will not qualify if you...

  • Current pregnancy
  • Current infection
  • Cervical dysplasia
  • History of transplant or transfusion
  • Cancer or history of cancer
  • Menopause
  • Age 38 or over for 6 controls without hysterectomy
  • Age 45 or over for 4 controls with hysterectomy
  • Endometriosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hopital Foch

Suresnes, France, 92151

Actively Recruiting

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Research Team

M

Marie Carbonnel, MD

CONTACT

E

Elisabeth Hulier-Ammar

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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Immunological Mechanisms of Rejection in Uterine Transplantation | DecenTrialz