Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT03080974

Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

Led by University of Louisville · Updated on 2025-10-29

10

Participants Needed

1

Research Sites

606 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Compare the efficacy and tolerability of irreversible electroporation in combination with Nivolumab in patients with locally advanced pancreatic cancer.

CONDITIONS

Official Title

Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Diagnosed with stage III pancreatic cancer
  • Tumor is measurable
  • Glomerular filtration rate greater than 60 mL/min/1.73 m²
  • Willing and able to follow the study protocol
  • Able to understand and sign informed consent
Not Eligible

You will not qualify if you...

  • Currently participating in another clinical trial for cancer treatment
  • Pregnant or breastfeeding
  • Have a cardiac pacemaker or implantable cardioverter defibrillator that cannot be turned off during the procedure
  • Have non-removable metal implants within 1 cm of the target tumor
  • Had a heart attack within 3 months before joining the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Louisville

Louisville, Kentucky, United States, 40202

Actively Recruiting

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Research Team

R

Robert Martin, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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