Actively Recruiting

Age: 19Years - 74Years
All Genders
NCT06796517

Immunotherapy in Lymphoma

Led by Sung-Soo Park · Updated on 2025-01-28

72

Participants Needed

2

Research Sites

79 weeks

Total Duration

On this page

Sponsors

S

Sung-Soo Park

Lead Sponsor

Y

Yeouido St. Mary's Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to compare the efficacy of advanced immunochemotherapy and classical immunochemotherapy in relapsed/refractory high grade B cell lymophoma patients. The main question it aims to answer is: Does advanced immunochemotherapy, including CAR-T therapy, bispecific antibody, and antibody-drug conjugate offer superior survival outcomes than when treated with classical immunochemotherapy, such as proteasome inhibitors, immune modulatory drugs, and monoclonal antibodies? Researchers will compare patients receiving advanced immunochemotherapy with those receiving classical immunochemotherapy to determine if advanced therapies result in better survival outcomes. Laboratory findings and electronic medical records (EMR) from participants will be used to assess survival outcomes and treatment-related safety profiles.

CONDITIONS

Official Title

Immunotherapy in Lymphoma

Who Can Participate

Age: 19Years - 74Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 19 to 74 years
  • Diagnosed after January 2015 with diffuse large B cell lymphoma, primary mediastinal large B cell lymphoma, high grade B cell lymphoma, or Burkitt lymphoma
  • Have received immunochemotherapy treatment for relapsed or refractory lymphoma
Not Eligible

You will not qualify if you...

  • Progression to acute leukemia
  • Development of solid tumor during treatment
  • Active infections including acute pneumonia, viral infections, active hepatitis B, or active pulmonary tuberculosis

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Seoul St. Mary Hospital

Seoul, South Korea, 06591

Actively Recruiting

2

Yeoido St. Mary Hospital

Seoul, South Korea, 07345

Actively Recruiting

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Research Team

S

Sung-Soo Park, MD. PhD.

CONTACT

Y

Young-Woo Jeon, MD. PhD.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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