Actively Recruiting
Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.
Led by Ciusss de L'Est de l'Île de Montréal · Updated on 2024-07-16
64
Participants Needed
1
Research Sites
46 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate esmolol's perfusion impact during induction and maintenance of general anesthesia, using Nociception-Level-guided control of nociception, in adult patients undergoing laparoscopic and lower abdominal surgery, on intraoperative remifentanil consumption and postoperative pain in the Post-Anesthesia Care Unit.
CONDITIONS
Official Title
Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fully consented adults aged 18 to 65 years with American Society of Anesthesiologists Classification Score 1 to 3
- Scheduled for laparoscopic surgery with a sub-umbilical mini-laparotomy, including hysterectomy (excluding vaginal approach) or left hemicolectomy
- Expected surgery duration under 180 minutes under general anesthesia
- No allergies to any medications used in the study
You will not qualify if you...
- Hypotension
- Sinus bradycardia
- Sick sinus syndrome
- Second and third degree atrioventricular block
- Pulmonary hypertension
- Right ventricular failure secondary to pulmonary hypertension
- Decompensated heart failure
- Cardiogenic shock
- Untreated pheochromocytoma
- Known hypersensitivity to esmolol or its ingredients
- Allergy to esmolol or other beta blockers
- Renal dysfunction
- Airway diseases such as asthma or chronic obstructive pulmonary disease
- Thyrotoxicosis
- Myasthenia gravis
- Raynaud's disease or peripheral circulatory disorder
- Severe mental impairment
- Chronic use of opioids or beta-adrenergic receptor antagonists
- High risk of conversion to laparotomy (>25%)
- Withdrawal of consent
- Conversion from laparoscopy to laparotomy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Maisonneuve-Rosemont Hospital - CIUSSS de l'Est de l'Île de Montréal
Montreal East, Quebec, Canada, H1T2M4
Actively Recruiting
Research Team
P
Pascal Laferrière-Langlois
CONTACT
N
Nadia Godin
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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