Actively Recruiting
Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study
Led by KidSIM Simulation Program · Updated on 2025-09-05
240
Participants Needed
4
Research Sites
65 weeks
Total Duration
On this page
Sponsors
K
KidSIM Simulation Program
Lead Sponsor
C
Canadian Institutes of Health Research (CIHR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study focuses on protecting healthcare workers (HCWs) from infection risks during aerosol-generating medical procedures (AGMPs) performed on critically ill COVID-19 patients. These procedures include bag-valve-mask ventilation, endotracheal intubation, and cardiopulmonary resuscitation (CPR), which can release virus-containing particles into the air. The research aims to evaluate the effectiveness of an aerosol box, a transparent barrier placed over the patient's head, in reducing contamination of HCWs during resuscitation while observing its impact on clinical task performance. Participants will be organized into teams including airway providers and CPR providers, who will perform simulated cardiac arrest scenarios either using the aerosol box device or without it. Teams will be trained and randomized to either the intervention group with aerosol box use or the control group without the box. The study includes video-based orientation, practice sessions, and randomized scenario order to assess the effect on CPR quality, intubation timing, airborne particle counts, and contamination. During the study, researchers will monitor team performance with multiple measurements including overall CPR quality, intubation success time, chest compression fraction, particle concentration near the patient, provider contamination area, and provider workload and anxiety. Data will be collected immediately after simulations, and participants will receive debriefing on performance and infection control. The study is designed to improve safety protocols for HCWs during pandemics by providing evidence about aerosol box use in a controlled simulated environment.
CONDITIONS
Brief Title
Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Attending physician, fellow, or resident in adult or pediatric emergency medicine, pediatric intensive care, general pediatrics, or pediatric/adult anesthesia
- Adult or Pediatric Advanced Life Support certification
- Attending physician, resident, fellow, nurse, respiratory therapist, physician assistant, or health care aide
- Basic Life Support, Adult or Pediatric Advanced Life Support certification
You will not qualify if you...
- Decline to provide informed consent
- Unable to perform tasks required of the role due to physical limitations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - Single session lasting approximately 1 to 2 hours
Participants work in teams to practice and perform simulated cardiopulmonary resuscitation scenarios with or without use of an aerosol box in a controlled simulation environment.
1 in-person visit including orientation, training, simulation scenarios, and debriefing
Trial Site Locations
Total: 4 locations
1
Department of Emergency Medicine, Children's Hospital of Los Angeles
Los Angeles, California, United States, 90027
Actively Recruiting
2
KidSIM, Alberta Children's Hospital
Calgary, Alberta, Canada, T3B6A8
Actively Recruiting
3
Department of Pediatrics, The Hospital for Sick Children
Toronto, Ontario, Canada
Actively Recruiting
4
Department of Pediatrics, CHU Sainte-Justine
Montreal, Quebec, Canada
Completed
Research Team
A
Adam Cheng, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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