Actively Recruiting

Age: 20Years - 60Years
All Genders
NCT06720246

Impact of Bariatric Surgery and Liraglutide on Cognitive-Behavioral Markers of Long-Term Weight Loss in Obesity

Led by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Updated on 2024-12-11

50

Participants Needed

1

Research Sites

148 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The present research project aims to study the effects of bariatric surgery and liraglutide administration (in patients already selected for one of these procedures) on two cognitive-behavioral processes partially supported by distinct brain networks: automatic approach tendencies (underpinned by the cue-reactivity network) and behavioral inhibition (underpinned by the cue-regulation network). Additionally, the investigators aim to study how these processes may be modulated by satiety. The secondary objective of the project includes identifying cognitive-behavioral markers that can predict the response to these treatments.

CONDITIONS

Official Title

Impact of Bariatric Surgery and Liraglutide on Cognitive-Behavioral Markers of Long-Term Weight Loss in Obesity

Who Can Participate

Age: 20Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects of any ethnicity, aged between 20 and 60 years
  • Body mass index (BMI) equal to or greater than 30 kg/m²
  • No history of neurological or psychiatric disorders, confirmed by medical history and neuropsychological screening
  • Signed informed consent and willingness to follow all study procedures
  • Patients scheduled for bariatric surgery, liraglutide treatment, or a dietary regimen
Not Eligible

You will not qualify if you...

  • Previous diagnosis of significant neurological conditions such as brain injury or dementia
  • Major psychiatric disorders
  • Current or past prolonged psychopharmacological therapy
  • Body mass index (BMI) lower than 30 kg/m²
  • Lack of signed informed consent
  • Severe medical conditions including hypertension, significant cardiac disease, or other disorders risking patient safety
  • Confirmed pregnancy or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Ospedale Galeazzi-Sant'Ambrogio

Milan, Milan, Italy, 20100

Actively Recruiting

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Research Team

E

Eraldo Paulesu, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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