Actively Recruiting
Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study
Led by AIDS Malignancy Consortium · Updated on 2026-01-23
100
Participants Needed
11
Research Sites
210 weeks
Total Duration
On this page
Sponsors
A
AIDS Malignancy Consortium
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial evaluates the usefulness of using a smartphone-based HIV-specific smoking cessation intervention at the time of lung cancer screening in helping people living with HIV quit smoking. Positively Smoke Free - Mobile may help patients with HIV quit smoking.
CONDITIONS
Official Title
Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to understand and willing to sign a written informed consent document
- HIV positive confirmed by medical record, antiretroviral therapy use, or licensed HIV testing
- Receiving antiretroviral therapy with a CD4 count of at least 200 cells/uL within 6 months
- Age between 45 and 80 years
- Current smoker confirmed by exhaled carbon monoxide level of 7 parts per million or higher
- Meets lung cancer screening criteria (age 50-80 with 20+ pack-years or age 45-49 with 20+ pack-years and high risk)
- Owns a smartphone capable of supporting the Positively Smoke Free Mobile app
- Has sufficient literacy (score 4 or higher on the REALM-R literacy scale)
You will not qualify if you...
- Currently using or used any other smoking cessation treatments within the past 30 days
- Contraindicated for nicotine replacement therapy
- Pneumonia or serious lung infection within the past 12 weeks
- Uncontrolled serious illness or psychiatric conditions limiting study compliance
- History of lung cancer
- Pregnant or breastfeeding women
- Had a chest CT scan within the previous 12 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
UC San Diego Moores Cancer Center
La Jolla, California, United States, 92093
Actively Recruiting
2
George Washington University
Washington D.C., District of Columbia, United States, 20052
Actively Recruiting
3
Moffitt Cancer Center
Tampa, Florida, United States, 33612
Actively Recruiting
4
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
5
Weill Cornell Medicine - Cornell Clinical Trials Unit
New York, New York, United States, 10010
Actively Recruiting
6
Mount Sinai Hospital
New York, New York, United States, 10029
Actively Recruiting
7
Montefiore Medical Center
The Bronx, New York, United States, 10461
Actively Recruiting
8
The Ohio State University James Cancer Hospital
Columbus, Ohio, United States, 43221
Actively Recruiting
9
Thomas Jefferson University
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
10
University of Texas M.D. Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
11
Virginia Mason Medical Center
Seattle, Washington, United States, 98101
Actively Recruiting
Research Team
K
Keith Sigel
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here