Study on How Blood-Injection-Injury Phobia Affects Fainting Risk During Upright Stress

What this Trial Is About

Researchers are studying how the bodys cardiovascular autonomic system responds to emotional triggers, specifically blood-injection-injury needle phobia, during an upright posture challenge. This study compares individuals with and without needle phobia to better understand why some people have low blood pressure reactions that can lead to fainting. Such reactions are common in medical settings and can cause avoidance of important health care, which impacts public health and healthcare systems. Participants will undergo a tilt test on two separate days in a randomized order. On one day, they will view images and videos related to blood-injection-injury phobia, and on the other day, they will see neutral content. Each exposure lasts about 498 seconds and begins two minutes before the upright tilt test. Cardiovascular responses will be closely monitored throughout the tests. During the study, volunteers will be assessed for cardiovascular control and tolerance to standing upright, measured by the time until near fainting occurs. Researchers will record heart and blood pressure changes while participants watch the videos and images. The main outcome is orthostatic tolerance, observed over a period of up to 50 minutes. The study aims to provide detailed insights into fainting susceptibility related to needle phobia and will run until December 2026.

Impact of Blood Phobia on Fainting Susceptibility