Actively Recruiting
Impact of Bone-Marrow Aspirate Injections in Knee Arthroscopy
Led by Hospital for Special Surgery, New York · Updated on 2026-04-27
50
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will examine whether using bone marrow aspirate (BMA) during knee arthroscopy surgery can improve patient outcomes. The investigators will enroll 50 patients who need knee arthroscopy surgery for meniscus injuries or cartilage damage. Like flipping a coin, patients will be randomly assigned to one of two groups of 25 patients each. One group will receive standard arthroscopic surgery plus an injection of bone marrow aspirate, while the other group will receive standard surgery plus a saline (salt water) injection. During surgery, for patients in the treatment group, approximately 4mL (less than one teaspoon) of bone marrow will be taken from their hip bone using a special needle system. A small amount (1mL) will be sent to the laboratory for testing. Patients will be followed for 12 months after surgery and will complete questionnaires about their pain levels and knee function at several time points: before surgery, 2 weeks, 6 weeks, 3 months, 6 months, and 12 months after surgery. These questionnaires will ask about pain, daily activities, and overall improvement.
CONDITIONS
Official Title
Impact of Bone-Marrow Aspirate Injections in Knee Arthroscopy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Require primary knee arthroscopy for meniscal injury or focal cartilage defect
- Kellgren-Lawrence grade 0 arthritis
- Outerbridge cartilage grade 2 or lower
- Aged 18 to 64 years
You will not qualify if you...
- Previous surgery on the same knee
- Kellgren-Lawrence grade 3 or higher arthritis
- Received orthobiologic treatments within 3 months before surgery
- Have ligament deficiencies
- Require meniscal repair
- Require osteotomy or other knee realignment surgery
- Used disease-modifying antirheumatic drugs (DMARDs) within last 3 months
- History of anemia, bleeding disorders, or inflammatory joint diseases
- History of metabolic bone diseases such as osteoporosis or Paget's disease
- Currently pregnant
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
Research Team
A
Akshay K Raghuram
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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