Actively Recruiting
Comparing Effects of Bupivacaine Diluted With 5% Dextrose or Saline on Infraclavicular Brachial Plexus Block Success and Pain Relief Duration
Led by Burçin Alaçam, MD · Updated on 2026-06-23
90
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
This research evaluates the effects of diluting the local anesthetic bupivacaine with either 5% dextrose in water D5W or 0.9% sodium chloride normal saline on the success and duration of infraclavicular brachial plexus blocks. The infraclavicular block is commonly used to provide anesthesia and pain relief for upper extremity surgeries. The study also examines secondary outcomes such as onset times for sensory and motor block, block quality, postoperative pain management needs, and safety measures. Participants will receive an ultrasound-guided infraclavicular block where bupivacaine is diluted in a 11 ratio with either D5W or saline to achieve a set injection volume, typically 30 mL. The block procedure is performed under sterile conditions by an experienced anesthesiologist. Two groups are compared one receiving bupivacaine diluted with D5W and the other with saline. The study monitors block success, sensory and motor block characteristics, analgesia duration, and postoperative analgesic requirements. During the study, sensory block onset will be assessed at multiple time points within the first 30 minutes after block administration using a pinprick test. Participants will report sensation differences compared to the opposite limb. Motor block duration will be tracked until full recovery, up to 24 hours post-surgery. Researchers will also record additional intraoperative anesthetic needs and postoperative pain control over 24 hours. The total participation duration extends through the surgery and postoperative monitoring periods.
CONDITIONS
Brief Title
Impact of Bupivacaine Dilution With Dextrose or Saline on Infraclavicular Block Outcomes
Research Team
B
Burçin Alaçam
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