Effect of Capsular Tension Ring Implantation on Postoperative IOL Position in Retinitis Pigmentosa Patients With Cataract: a Multi-center, Randomized, Self-controlled Study

What this Trial Is About

This research aims to study the effects of capsular tension ring (CTR) implantation on the position of intraocular lenses (IOL) in patients with cataracts who also have retinitis pigmentosa (RP). RP patients often face higher risks during cataract surgery due to issues like zonular weakness and vitreous changes, which can cause IOL tilt, decentration, and capsular contraction. This trial is designed as a randomized, self-controlled study where each patient serves as their own control, allowing direct comparison between eyes. Participants will undergo bilateral cataract surgery. One eye will receive a combined implantation of a monofocal IOL (J&J Tecnis DCB00) and a capsular tension ring (CTR), while the other eye will receive only the IOL. The CTR is implanted after removing the lens nucleus and cortex using standard phacoemulsification through a small corneal incision, aiming to support the capsular bag and zonules. Follow-up visits are scheduled at 1 week, 1 month, 3 months, 6 months, and 1 year after surgery to monitor outcomes. During follow-up visits, researchers will measure IOL decentration and tilt using anterior segment SS-OCT imaging (Casia 2), assess visual acuity, and record any postoperative complications. The primary outcome is IOL decentration measured at 3 months post-surgery. Secondary outcomes include additional measurements of IOL position, visual acuity, and complications at multiple time points. The total study duration for each participant is one year post-surgery.

Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients