Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID07506798

Effects of Combined Intravenous-Inhalational Anesthesia Versus Inhalational Anesthesia on Postoperative Recovery in Gynecological Surgery Based on QoR-15 Scores

Led by Sakarya University · Updated on 2026-04-02

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of combined intravenous-inhalational anesthesia compared to inhalational anesthesia alone on recovery after elective gynecologic surgery. The study includes 100 patients aged 18 to 65 years classified as ASA physical status I to III. They will measure recovery using the Quality of Recovery-15 (QoR-15) questionnaire, which assesses physical comfort, emotional state, psychological support, pain, and daily activity ability. Higher scores reflect better recovery. Participants will be randomly assigned to receive either combined intravenous-inhalational anesthesia or inhalational anesthesia only during their surgery. Both groups will follow routine clinical practice for anesthetic drugs and doses. Postoperative recovery will be evaluated using the QoR-15 questionnaire on postoperative days 1 and 2. Secondary outcomes include pain scores at postoperative hours 6, 12, and 24, incidence of nausea and vomiting within 24 hours after surgery, and length of stay in the post-anesthesia care unit. During the study, patients will complete the QoR-15 questionnaire before surgery without knowing their anesthesia type and again on days 1 and 2 after surgery. Intraoperative data will be collected from anesthesia records. Researchers will monitor recovery quality, pain levels, nausea and vomiting occurrence, and care unit stay length to assess anesthesia impact. Participation lasts from pre-surgery through postoperative day 2, with monitoring up to 10 days for some outcomes.

CONDITIONS

Brief Title

Impact of Combined Intravenous-Inhalational vs Inhalational Anesthesia on QoR-15 Recovery Scores in Gynecologic Surgery

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18-65 years
  • Scheduled for elective gynecologic surgery at Sakarya University Faculty of Medicine Training and Research Hospital
  • Classified as ASA physical status I, II, or III
  • Able to understand and complete the QoR-15 questionnaire
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Severe comorbidities beyond ASA physical status III
  • Advanced neurological disease or cognitive impairment
  • Known allergy to anesthetic drugs used in the study
  • Classified as ASA physical status IV or V
  • Refusal to participate in the study
  • Emergency or urgent surgery

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Duration - Day of surgery

Participants receive either combined intravenous-inhalational anesthesia or inhalational anesthesia only during elective gynecologic surgery, following routine clinical practice.

1 surgical visit (in-person)

Post-operative Follow-up

Duration - 2 days

Participants' recovery is assessed using the Quality of Recovery-15 (QoR-15) questionnaire on postoperative days 1 and 2, along with monitoring of pain scores, nausea and vomiting, and length of stay in the post-anesthesia care unit.

Assessments on postoperative days 1 and 2 with additional monitoring up to 10 days

Trial Site Locations

Total: 1 location

1

Sakarya University Training and Research Hospital

Sakarya, Turkey (Türkiye), 54290

Actively Recruiting

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Research Team

M

melike kar ünlü, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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