Actively Recruiting

Phase Not Applicable
Age: 18Years - 38Years
FEMALE
NCT02948972

Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility

Led by University Hospital, Lille · Updated on 2026-04-22

120

Participants Needed

5

Research Sites

493 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Lille

Lead Sponsor

M

Ministry of Health, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)

CONDITIONS

Official Title

Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility

Who Can Participate

Age: 18Years - 38Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Primary or secondary infertility
  • Indication for IVF treatment
  • Persistent pain related to endometriosis despite medical pain treatment
  • Persistent pain including at least one digestive symptom related to endometriosis: dyschesia, sub-occlusive syndrome, rectal bleeding, or painful defecation
  • Colorectal deep infiltrating endometriosis confirmed by MRI and at least one additional imaging method
  • Eligible for deep infiltrating endometriosis surgery
Not Eligible

You will not qualify if you...

  • Contraindication to pregnancy or IVF
  • Viral risk
  • Previous IVF cycles
  • Previous colorectal surgery
  • Need for myomectomy during surgery
  • Use of donor oocytes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

CHU

Clermont-Ferrand, France

Actively Recruiting

2

Hôpital Jeanne de Flandres, CHRU

Lille, France

Actively Recruiting

3

AP-HP, Hôpital Tenon

Paris, France

Actively Recruiting

4

CHU

Poissy, France

Actively Recruiting

5

CHU

Rouen, France

Actively Recruiting

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Research Team

P

Pierre Collinet, MD,PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility | DecenTrialz