Actively Recruiting
Impact of Compression Garments on Neuropathic-looking Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs
Led by Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape · Updated on 2025-10-06
60
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
Sponsors
C
Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Lead Sponsor
C
Clinique Mutualiste Lorient
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the use of compression garments to reduce neuropathic pain in people with Complex Regional Pain Syndrome (CRPS) of the upper limbs. This condition can involve pain and swelling, and while compression garments are used to reduce swelling, their effect on neuropathic pain is not well established. The study aims to explore whether wearing these garments can notably reduce pain, based on clinical experience and patient reports. Participants will receive usual care in day hospitals, consisting of three occupational therapy sessions per week for three months. One group will also wear compression garments during this period, while the other group will receive the same care without compression garments. The therapy includes desensitization using devices such as Aquaroll and Vibralgic. Follow-up visits will occur at six months and one year to continue assessments. During the study, pain will be measured weekly using a Visual Analog Scale (VAS) over three months, along with monitoring the tolerance and adherence to wearing the compression garments. Additional evaluations include range of motion, muscle strength, sensitivity tests, anxiety and depression assessments, quality of life surveys, and pain questionnaires. Researchers will track changes in medication, hand circumference, and disability scores. The total participation time includes the initial three-month treatment period plus follow-ups at six months and one year.
CONDITIONS
Brief Title
Impact of Compression Garments on Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with Complex Regional Pain Syndrome (CRPS) of the upper limb with neuropathic pain
- Diagnosis of CRPS according to the Budapest criteria
- Diagnosis of neuropathic pain according to DN4
- CRPS evolving for more than 3 months
- No phlebitis or open sores on the upper limbs
- Patient consents to participate in the study
- No change in drug treatment for 1 month before the study
- Affiliated with a social security scheme or beneficiary of such a scheme
You will not qualify if you...
- Patient under guardianship, curatorship, or safeguard of justice
- Psychiatric illness that affects ability to consent
- Severe cognitive disorders preventing pain assessment
- Skin conditions preventing wearing compression garments
- Previous use of compression garments
- History of vascular disorders, lymph node dissection, or other causes of edema in upper limbs
- Known allergy to components of Cerecare compression garments
- Pregnancy, breastfeeding, or woman of childbearing potential without contraception
- Unable to put on the compression garment alone
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 3 months
Participants receive usual care in day hospitals with 3 occupational therapy sessions per week for 3 months, including desensitization protocols. Participants in the experimental group also wear compression garments for 3 months. Pain, tolerance, and compliance with compression garments are assessed weekly during this period.
Weekly visits for 3 months
Duration - Up to 1 year from start
Participants attend follow-up consultations at 6 months and 1 year after the start of the study. Various assessments are carried out during these visits including pain, range of motion, muscle strength, sensitivity tests, anxiety, depression, and quality of life.
2 visits (at 6 months and 1 year)
Trial Site Locations
Total: 1 location
1
CMRRF de Kerpape
Ploemeur, Brittany Region, France, 56270
Actively Recruiting
Research Team
V
Vincent Detaille, Doctor
M
Marie-Caroline Delebecque, CRA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here