Actively Recruiting
Impact OF Cooled Versus Thermal Radiofrequency Denervation In Management Of Chronic Lumber Facet Joint Pain
Led by Zagazig University · Updated on 2026-01-06
100
Participants Needed
2
Research Sites
37 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chronic lumber facet joint pain is defined according to international association of study of pain (IASP)as multifactorial phenomenon of pain that persist more than 3 months after an injury and /or beyond the usual course of an acute lumber facet pain or a reasonable time for a comparable injury to heal . lumber facet joint degeneration (LRFJ) is the 1st source of chronic low back pain with an incidence of 15% t o 45 % among patients with low back pain . the spinal facet joint has an abundant nerve supply ; therefore, pain can be caused by arthritic change, degenerative change, inflammation, and injury . Degeneration of all LFJs (lumbar facet joints) was diagnosed using magnetic resonance image (MRI) , the most sensitive and diagnostic tool. Thus, hypertrophy, degeneration, and the accumulation of fluid within the joints are signs of LFJ degeneration it was found in all treated LFJs . facet joint pain management can be achieved using medical therapy or facet joint therapeutic interventions, ultrasound guided injection,or fluoroscopically guided facet joint injection (FJI) , medial branch block (MBB) , or radiofrequency ablation . Radiofrequency is a minimally invasive procedure and is operated under light intravenous sedation or local anesthesia when necessary. Radiofrequency energy is delivered to the target nerves through an insulated needle , and this energy heats and denatures the nerve for the purpose of pain relief . The radiofrequency techniques include, thermal, and cooled radiofrequency . thermal radiofrequency (TRFA) uses more energy and higher temperature compared with cooled radiofrequency , cooled radiofrequency ablation (CRFA) is a newer technique, and may have some theoretical advantages over traditional radiofrequency whereas , cooled radiofrequency adopts internally probes to increase lesion size , and it can increase the chance of complete denervation . based on heat neurotomy (60°C (celsius) vs. 80°C in TRFA) with the resulting ablative area twice as long and extending distally from the tip of the electrode.
CONDITIONS
Official Title
Impact OF Cooled Versus Thermal Radiofrequency Denervation In Management Of Chronic Lumber Facet Joint Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient's acceptance
- Both sexes (male and female)
- Age between 30 and 70 years
- Physical status ASA I or II (American Society of Anesthesiologists)
- Body mass index (BMI) between 22 and 30 Kg/m2
- Chronic lumbar facet joint pain with numerical rating scale (NRS) 6 or higher lasting 3 months or more
- No response to noninvasive conservative treatments such as NSAIDs, gabapentin, or physiotherapy
- Two to three levels of bilateral facet arthropathy with normal motor power in lower extremities
- Local paraspinal tenderness with increased pain on hyperextension, rotation, or lateral bending of the lower lumbar spine
- At least 50% temporary pain relief after ultrasound-guided diagnostic medial branch block with local anesthetic corticosteroid injection
You will not qualify if you...
- Presence of spondylolisthesis, disc herniation, or internal disc disruption (IDD)
- Previous spinal surgery at the treated level
- Spinal canal stenosis or spinal instability
- Previous radiofrequency ablation treatment
- Radicular pain, neurogenic claudication, or neurological deficits
- Coagulopathy or bleeding disorders
- Allergy to medications or contrast agents used
- Rheumatic disorders
- Systemic or local infections in the intervention area
- Any uncontrolled medical or psychiatric conditions
- Pregnancy or lactation
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Trial Site Locations
Total: 2 locations
1
Faculty of Medicine,Zagazig University
Zagazig, Elsharqya, Egypt, 44519
Actively Recruiting
2
Faculty of Medicine,Zagazig University
Zagazig, Elsharqya, Egypt, 44519
Actively Recruiting
Research Team
M
manal M rashad, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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