Actively Recruiting
Impact of the Corrie Lipids Digital Health Program on Lipid Optimization
Led by Johns Hopkins University · Updated on 2026-03-18
1000
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
A
Amgen
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overall objective is to evaluate the effectiveness and implementation of the Corrie Lipids Program, a comprehensive digital health initiative designed to address critical gaps in lipid-lowering as a component of ASCVD treatment by delivering an intervention that combines a patient-facing smartphone app, clinician education and coaching, and seamless incorporation into clinical workflows. Researchers plan to assess this multicenter digital health initiative in approximately 1,000 adults with uncontrolled LDL-C and elevated ASCVD risk using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. The study will examine whether the program improves LDL-C goal attainment, app engagement, prescribing patterns, and LDL-C monitoring, while also identifying barriers and facilitators to implementation across sites.
CONDITIONS
Official Title
Impact of the Corrie Lipids Digital Health Program on Lipid Optimization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Uncontrolled LDL cholesterol according to AHA/ACC guidelines
- At least one major cardiovascular risk factor, including high ASCVD risk, known or subclinical ASCVD, familial hypercholesterolemia or LDL-C ≥190 mg/dL, diabetes mellitus, or history of statin side effects
- Has a primary care physician and/or cardiologist able to prescribe lipid therapy
- Owns a smartphone and agrees to use the digital health app
- Provided informed consent before starting study activities
You will not qualify if you...
- Motor, cognitive, auditory, or visual impairments limiting technology use
- Does not speak English
- Malignancy except nonmelanoma skin cancers or certain breast/cervical cancers within 5 years
- Pregnancy, planning pregnancy, egg donation, breastfeeding, or planning to breastfeed
- Unlikely to comply with study procedures
- Any other clinically significant condition that may pose safety risks or interfere with study evaluation or completion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
F
Francoise Marvel, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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