Impact of Creatine Monohydrate Micronized Supplementation With or Without Multicomponent Training in Older Adults

What this Trial Is About

Researchers are evaluating whether creatine supplementation, with or without a multicomponent exercise program, can improve physical function and cognitive abilities in people over 75 years old. The study aims to understand if creatine alone or combined with strength, balance, and walking exercises can provide benefits and if it is safe for older adults. This research hopes to improve quality of life for elderly patients and support better healthcare strategies. Participants are randomly assigned to one of four groups: creatine supplementation alone, placebo supplementation alone, placebo with exercise, or creatine with exercise. The multicomponent training includes supervised sessions focused on strength, balance, and walking tailored to each participant's abilities. The exercise program happens several times a week, and creatine or placebo is taken alongside. The intervention lasts around 5 weeks, with follow-up assessments after discharge. During the study, participants undergo tests measuring physical function, strength, and cognition using standardized tools like the Timed Up and Go Test and Mini-Mental State Examination. Quality of life is assessed through surveys before and after the intervention. Follow-up visits at 5 weeks post-discharge track progress to capture any lasting benefits. Safety and muscle status are also monitored throughout the approximately 10-week study period.

Impact of Creatine Monohydrate Micronized Supplementation With or Without Multicomponent Training in Older Adults.