Actively Recruiting
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Led by West China Hospital · Updated on 2024-06-04
890
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality. Anaesthetic drugs can also affect postoperative cognition, as their residual effects can alter central nervous system activity. Desflurane and sevoflurane are widely used volatile anesthetics. Choice anesthetics may influence the occurrence of postoperative delirium. However, evidence in this aspect is conflicting.
CONDITIONS
Official Title
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 years or older and less than 90 years
- Scheduled for non-cardiac and non-neurosurgery lasting 2 hours or more under general anesthesia
- Willing to participate and able to provide signed written informed consent
You will not qualify if you...
- History of schizophrenia, epilepsy, parkinsonism, or any central nervous system disease before surgery
- Unable to communicate before surgery due to coma, dementia, language barrier, impaired hearing, or vision
- Severe heart, lung, liver, or kidney disease, or physical status of American Society of Anesthesiologists classification IV or higher
- Alcoholism or drug dependence
- Any other condition deemed unsuitable for participation by surgeons or investigators, with reasons documented
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Anesthesiology, West China Hospital
Chengdu, Sichuan, China, 610041
Actively Recruiting
Research Team
J
Jing Yang, MD,PhD
CONTACT
M
Min Xu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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