Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
Healthy Volunteers
NCT05931562

The Impact of Diet on the Gut-Microbiota-Brain Axis

Led by University College Cork · Updated on 2024-07-16

200

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to investigate the effects of an 8-week dietary intervention on cognitive function, stress, and the gut microbiota in healthy adults with low fibre intake.

CONDITIONS

Official Title

The Impact of Diet on the Gut-Microbiota-Brain Axis

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to give written informed consent
  • Aged between 18 and 50 years
  • Have a body mass index (BMI) between 18.5 and 29.9 Kg/m2
  • Be generally healthy as determined by the investigator
Not Eligible

You will not qualify if you...

  • Younger than 18 or older than 50 years
  • BMI below 18.5 or above 29.9 Kg/m2
  • Have significant acute or chronic illnesses including cardiovascular, gastrointestinal (such as functional GI disorders, inflammatory bowel disease, coeliac disease, lactose intolerance, food allergies), immunological, psychiatric (including major depression, anxiety disorder, bipolar disorder, schizophrenia, other DSM-IV Axis I disorders), neurodevelopmental, metabolic (including diabetes type I or II), or any condition that contraindicates study entry
  • Taking medications or having conditions that may interfere with study objectives or pose safety risks, including psychoactive medications, laxatives, enemas, antibiotics, anticoagulants, over-the-counter NSAIDs, with required 4-week washout
  • Currently using prebiotic or probiotic supplements without 4-week washout
  • Females who are peri-menopausal, menopausal, or post-menopausal
  • Pregnant, planning pregnancy, or lactating females
  • Not fluent in English
  • Color blind
  • Have dyslexia or dyscalculia
  • Current habitual daily smoker
  • Considered unlikely to comply with the study by the investigator
  • Receiving treatment with experimental drugs or recently completed experimental trials within 30 days
  • Have malignant disease or end-stage organ disease
  • Participated in a laboratory study at this site within the past 4 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

APC Microbiome Ireland

Cork, Ireland, T12YT20

Actively Recruiting

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Research Team

E

Elizabeth Schneider, PhD

CONTACT

R

Revathy Munuswamy

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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The Impact of Diet on the Gut-Microbiota-Brain Axis | DecenTrialz